Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Caspase-2 monoclonal antibody (10C6)

ALX-804-355-C100 100 µg 487.00 USD
Do you need bulk/larger quantities?

Product Details

Immunogen:Recombinant human caspase-2 (p19 subunit).
UniProt ID:P42575
Species reactivity:Human, Mouse, Rat
Dog, Monkey
Specificity:Recognizes an epitope in the p19 subunit of human, mouse, rat, monkey and dog caspase-2.
Applications:ELISA, Flow Cytometry, ICC, IHC (FS)
Recommended Dilutions/Conditions:Flow Cytometry (1µg/ml)
Immunocytochemistry (10-20µg/ml; fix in 4% paraformaldehyde, 0.18% Triton-X100 for 10 min. prior to staining)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein G-affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment: M. Lopez-Cruzan, et al.; Cell Death Discov. 2, 16005 (2016), Application(s): Immunocytochemistry, Abstract; Full Text
Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death: V.S. Marsden, et al.; Blood 107, 1872 (2006), Abstract; Full Text
Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation: C.L. Scott, et al.; J. Cell Biol. 164, 89 (2004), Abstract; Full Text
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9: L.A. O’Reilly, et al.; Cell Death Differ. 9, 832 (2002), Abstract; Full Text

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
Caspase Monoclonal antibody
Caspase-2 Monoclonal antibody
By catalog section:


Technical Service
Customer Service