Product Details
Alternative Name: | CD95L, APO-1L, CD178, TNFSF 6 |
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Clone: | 3C82 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Recombinant human FasL (APO-1L; CD95L; CD178) (extracellular domain). |
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UniProt ID: | P48023 |
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Species reactivity: | Human, Mouse
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Applications: | Flow Cytometry, FUNC
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Recommended Dilutions/Conditions: | Suggested starting dilution is >1:100 Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Functional Application: neutralizing |
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Purity Detail: | Epitope-affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.2, containing 1% BSA. Contains no preservatives. |
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Handling: | Do not freeze. |
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Shipping: | Blue Ice |
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Long Term Storage: | +4°C |
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Regulatory Status: | RUO - Research Use Only |
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Schematic structure of recombinant human FasL (extracellular domain).
Figure: Inhibition of mouse FasL (supernatant of FasL-transfected Neuro2A cells) by 3C82.Method: Supernatants of Neuro2A cells containing murine FasL (1:2 dilution) were incubated with Fas ecpressing L929-APO-1 target cells. After 14h apoptosis was assessed by MTT staining.
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Product Literature References
Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells: J.E. Dalton, et al.; J. Immunol.
173, 3660 (2004),
Abstract;
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