Product Details
Alternative Name: | TRANCE-R, ODFR, TNFRSF 11A, CD265 |
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Clone: | 9A725 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Recombinant human RANK (aa 326-616). |
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UniProt ID: | Q9Y6Q6 |
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Species reactivity: | Human, Mouse
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Specificity: | Recognizes an epitope between aa 330-427. |
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Applications: | Flow Cytometry, IHC (PS), WB
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Recommended Dilutions/Conditions: | Flow Cytometry (intracellular) Western Blot (1-2µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~97kDa by Western blot. |
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Positive Control: | Activated T cells can be used as positive control. |
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Purity Detail: | Protein G-affinity purified. |
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Formulation: | Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Technical Info/Product Notes: | Replacement for ADI-AAM-405 |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Western blot analysis of RANK in 293 cells transfected with RANK cDNA. A single protein band of of ~97kDa was detected.
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Product Literature References
A novel in vivo role for osteoprotegerin ligand in activation of monocyte effector function and inflammatory response: D. Seshasayee, et al.; J. Biol. Chem.
279, 30202 (2004),
Abstract;
Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism: A.C. Bharti, et al.; J. Biol. Chem.
279, 6065 (2004),
Abstract;
Full Text
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines: P. Fiumara, et al.; Blood
98, 2784 (2001),
Abstract;
Full Text