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Troy (human) monoclonal antibody (Giu.Li)

ALX-804-146-C050 50 µg 373.00 USD
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Product Specification

Alternative Name:TAJ, TNFRSF 19
Immunogen:Recombinant human Troy cysteine-rich domain (aa 1-168).
UniProt ID:Q9NS68
Source:Purified from concentrated hybridoma tissue culture supernatant.
Species reactivity:Human
Applications:Flow Cytometry
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
Troy (human) monoclonal antibody (Giu.Li) Flow Cytometry
Figure: HEK 293T cells were mock transfected (thin line) or transfected with an expression coding for the extracellular domain of human Troy (thick line).
Method: Cells (5x105) were incubated on ice for 30 min in 50µl FACS buffer (PBS, 5% Fetal calf serum, 0.02% azide) containing 1µg/ml of monoclonal antibody to Troy (Giu.Li). After washing in FACS buffer, R-PE-conjugated antibody to rat IgG (Prod. No. ALX-211-053) was added. Cells were incubated on ice for 30 min, washed and analyzed by flow cytometry."
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Troy (human) monoclonal antibody (Giu.Li) Flow Cytometry

General Literature References

TRAF6-deficient mice display hypohidrotic ectodermal dysplasia: A. Naito, et al.; PNAS 99, 8766 (2002), Abstract; Full Text
TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death: M.T. Eby, et al.; J. Biol. Chem. 275, 15336 (2000), Abstract; Full Text
TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles: T. Kojima, et al.; J. Biol. Chem. 275, 20742 (2000), Abstract; Full Text

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