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H⁺/K⁺ ATPase-β monoclonal antibody (2G11)



ALX-804-084-R100	100 µl	580.00 USD
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Product Details

Alternative Name:	Potassium-transporting ATPase subunit β

Clone:	2G11

Host:	Mouse

Isotype:	IgG1

Immunogen:	Purified 34kDa core peptide from deglycosylated pig gastric microsomes.

UniProt ID:	P18434 (pig), P51164 (human)

Species reactivity:	Human, Mouse, Rat Bovine, Dog, Ferret, Porcine, Rabbit

Specificity:	Recognizes the β subunit of H⁺/K⁺ ATPase.

Applications:	ICC, IHC (FS), IHC (PS), IP, WB, FUNC

Recommended Dilutions/Conditions:	Immunocytochemistry (1:2,000) Immunohistochemistry (paraffin and frozen sections, 1:2,000) Western Blot (1:4,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Application Notes:	Functional Application: Inhibits enzymatic activity of H⁺/ K⁺ ATPase and alters affinity of its cytoplasmic potassium binding site.

Formulation:	Liquid. PBS-diluted ascites containing 0.05% sodium azide.

Handling:	Avoid freeze/thaw cycles.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only

Product Literature References

Localization and function of soluble N-ethylmaleimide-sensitive factor attachment protein-25 and vesicle-associated membrane protein-2 in functioning gastric parietal cells: S. Karvar, et al.; J. Biol. Chem. 277, 50030 (2002), Abstract; Full Text

Functionally distinct pools of actin in secretory cells: D.A. Ammar, et al.; Am. J. Physiol. Cell Physiol. 281, C407 (2001), Abstract; Full Text

Expression of rab11a N124I in gastric parietal cells inhibits stimulatory recruitment of the H+-K+-ATPase: J.G. Duman, et al.; Am. J. Physiol. 277, C361 (1999), Abstract; Full Text