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HSC70 monoclonal antibody (13D3)

ALX-804-067-R050 50 µl 710.00 USD
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Product Details

Alternative Name:Heat shock cognate protein 70
Immunogen:Mouse spermatogenic cell protein.
UniProt ID:P63017
Species reactivity:Human, Mouse, Rat
Cat, Monkey
Crossreactivity:Slightly cross-reacts with HSP70.
Applications:IF, IHC, IP, WB
Recommended Dilutions/Conditions:Immunofluorescence (1:20-1:200)
Immunohistochemistry (frozen sections, 1:20-1:200)
Immunoprecipitation (2 µl)
Western Blot (1:1,000-1:5,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~70kDa by Western blot.
Formulation:Liquid. Ascites diluted in PBS containing 0.05% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Stimulation of mTOR-independent autophagy and mitophagy by rilmenidine exacerbates the phenotype of transgenic TDP-43 mice: N.D. Perera, et al.; Neurobiol. Dis. 154, 105359 (2021), Abstract;
Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET: J. Kim, et al.; Elife 7, e39944 (2018), Abstract; Full Text
The blue light-induced interaction of cryptochrome 1 with COP1 requires SPA proteins during Arabidopsis light signaling: X. Holtkotte, et al.; PLoS Genet. 13, e1007044 (2017), Abstract; Full Text
Registered report: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET: J. Lesnik, et al.; eLife 5, e07383 (2016), Application(s): Western blot, Abstract;
E3 ligase CHIP and Hsc70 regulate Kv1.5 protein expression and function in mammalian cells: P. Li, et al. ; J. Mol Cell. Cardiol. 86, 138 (2015), Application(s): Kv1.5 Degradation ,
Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies: J. Saliba, et al. ; Nat. Genet. 47, 1131 (2015), Application(s): Immunoblotting, Abstract;
Heat-shock cognate protein (hsc71) and related proteins in mouse spermatogenic cells: M. Maekawa, et al.; Biol. Reprod. 40, 843 (1989), Abstract;

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