Product Details
Alternative Name: | PR |
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Clone: | αPR6 |
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Host: | Mouse |
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Isotype: | IgG2a |
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Immunogen: | Purified chicken PR (progesterone receptor). |
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UniProt ID: | P07812 |
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Species reactivity: | Human, Mouse, Rat Bovine, Chicken, Guinea pig, Rabbit, Sheep
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Specificity: | Recognizes the B form of PR. |
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Crossreactivity: | Does not cross-react with ER (estrogen receptor) or GR (glucocorticoid receptor). |
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Applications: | ICC, IHC (FS), IHC (PS), IP, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (frozen sections, 20µg/ml) Immunohistochemistry (paraffin sections, 5µg/ml) Western Blot (1µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~110kDa in chicken and rabbit, and a doublet or triplet band of ~120kDa in human by Western blot. |
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Purity Detail: | Purified IgG2a from ascites. |
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Formulation: | Lyophilized. Contains 0.05% sodium azide. |
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Reconstitution: | Reconstitute with PBS. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Avian and mammalian PR isolated from tissue soluble extracts can exist in one of two different molecular forms A and B. Human PR consists of a 94kDa A form and a 120kDa B form. Chicken PR consists of a 78kDa A form and a 110kDa B form. Alpha PR6 reacts with both the 120kDa B form of human PR and the 110kDa B form of chicken PR. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Ovine uterine gland knock-out model: effects of gland ablation on the estrous cycle: C. Allison Gray, et al.; Biol. Reprod.
62, 448 (2000),
Abstract;
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