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Breast cancer resistance protein monoclonal antibody (BXP-53)

ALX-801-036-C050 50 µg 419.00 USD
ALX-801-036-C100 100 µg 698.00 USD
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Product Details

Alternative Name:BCRP, ABCG2, MXR, CD338
Immunogen:Recombinant mouse BCRP (breast cancer resistance protein; MXR) (aa 221-394).
UniProt ID:Q7TMS5
Species reactivity:Human, Mouse
Specificity:Recognizes an internal epitope of BCRP.
Applications:ICC, IHC (FS), IHC (PS), WB
Recommended Dilutions/Conditions:Immunocytochemistry: Use 1:20-1:50 dilution on acetone fixed cytospin preparations.
Immunohistochemistry (frozen sections, paraffin sections): Use 1:20 on acetone fixed frozen sections followed by incubation with biotin-labelled rabbit anti-rat IgG and HRP-labelled streptavidin., Western Blot: Use 1:20-1:50 dilution and HRP-labelled anti-rat IgG.
Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.
Formulation:Liquid. In PBS, containing 0.1% BSA, and 0.02% sodium azide.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier: H. Chapy, et al.; Br. J. Pharmacol. 173, 497 (2016), Abstract; Full Text
Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice: A. Brenn, et al.; Int. J. Alzheimers Dis. 2011, 690121 (2011), Application(s): IHC using mouse brain tissue, Abstract; Full Text
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria: J.W. Jonker, et al.; PNAS 99, 15649 (2002), Abstract; Full Text

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