Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

MRP1 (human) monoclonal antibody (QCRL-3)

ALX-801-011-L001 1 ml 411.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:Multidrug resistance-associated protein 1, ABCC1
Immunogen:Membranes prepared from the human small cell lung cancer cell line H69AR.
UniProt ID:P33527
Species reactivity:Human
Specificity:Recognizes a conformation-dependent internal epitope (aa 617-932) of human MRP1 (multidrug resistance-associated protein 1), overexpressed in various human non-P-glycoprotein MDR tumor cell lines.
Crossreactivity:Does not cross-react with human P-glycoprotein, MDR3 P-glycoprotein, or mouse MRP gene products.
Applications:Flow Cytometry, ICC, IHC (PS), IP, FUNC
Application Notes:Flow Cytometry: cell permeabilization required
Immunocytochemistry: cytospin preparations
Functional Application: inhibits LTC4 transport
Not recommended for Western blot.
Formulation:Liquid. 0.22µm-filtered antibody in PBS containing 0.7% BSA and 0.1% sodium azide.
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1: J. Renes, et al.; Br. J. Pharmacol. 126, 681 (1999), Abstract;
Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein: D.R. Hipfner, et al.; J. Biol. Chem. 274, 15420 (1999), Abstract; Full Text
MRP expression in acute myeloid leukemia. An update: M. Filipits, et al.; Adv. Exp. Med. Biol. 457, 141 (1999), Abstract;
Structural, mechanistic and clinical aspects of MRP1: D.R. Hipfner, et al.; Biochim. Biophys. Acta 1461, 359 (1999), Abstract;
MRP and MDR1 gene expression in primary breast carcinomas: M. Filipits, et al.; Clin. Cancer Res. 2, 1231 (1996), Abstract;
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport: D.W. Loe, et al.; J. Biol. Chem. 271, 9675 (1996), Abstract; Full Text
Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell: K.C. Almquist, et al.; Cancer Res. 55, 102 (1995), Abstract;
Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies: D.R. Hipfner, et al.; Cancer Res. 54, 5788 (1994), Abstract;

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
MRP Monoclonal antibody
By catalog section:


Technical Service
Customer Service

Related Literature

Product Flyers
Detect Activity of Major ABC Transporter Proteins
Detect Activity of Major ABC Transporter Proteins
Download as PDF

All new literature pieces

Keep in touch

©2022 Enzo Life Sciences, Inc.,