Phytotoxin. Causes plant cell necrosis at nanomolar concentrations. Demonstrated to be produced by bacterial nitric oxide synthases (NOS).
Product Details
| Alternative Name: | Thaztomin A |
| |
| Formula: | C22H22N4O6 |
| |
| MW: | 438.4 |
| |
| Source: | Isolated from Streptomyces bottropensis. |
| |
| CAS: | 122380-18-1 |
| |
| Purity: | ≥98% (HPLC) |
| |
| Identity: | Determined by 1H-NMR. |
| |
| Appearance: | Yellow powder. |
| |
| Solubility: | Soluble in DMSO or dimethyl formamide; partially soluble in methanol or 100% ethanol; |
| |
| Shipping: | Shipped on Blue Ice |
| |
| Short Term Storage: | +4°C |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
| |
| Handling: | After reconstitution protect from light at -20°C. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Thaxtomin A induces programmed cell death in Arabidopsis thaliana suspension-cultured cells: I. Duval, et al.; Planta
222, 820 (2005),
Abstract;
Nitration of a peptide phytotoxin by bacterial nitric oxide synthase: J.A. Kers, et al.; Nature
429, 79 (2004),
Abstract;
An Arabidopsis mutant resistant to thaxtomin A, a cellulose synthesis inhibitor from Streptomyces species: W.R. Scheible, et al.; Plant Cell
15, 1781 (2003),
Abstract;
Full Text
More chemistry of the thaxtomin phytotoxins: R.R. King, et al.; Phytochemistry
64, 1091 (2003),
Abstract;
Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies: F.G. Healy, et al.; J. Bacteriol.
184, 2019 (2002),
Abstract;
Full Text
Selection and characterization of microorganisms utilizing thaxtomin A, a phytotoxin produced by streptomyces scabies: C.L. Doumbou, et al.; Appl. Environ. Microbiol.
64, 4313 (1998),
Abstract;
Full Text
