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T-2 Toxin

Monoamine oxidase inhibitor
ALX-630-101-M001 1 mg 58.00 USD
ALX-630-101-M005 5 mg 216.00 USD
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Mycotoxin. Induces DNA damage and apoptosis. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in the brain.

Product Details

Alternative Name:4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
Source:Isolated from Fusarium Sporotrichoides.
Purity:≥98% (TLC)
Appearance:White to off-white crystalline solid.
Solubility:Soluble in methylene chloride (5mg/ml) or chloroform.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Iturin A Strongly Inhibits the Growth and T-2 Toxin Synthesis of Fusarium oxysporum: A Morphological, Cellular, and Transcriptomics Study: M. Hua, et al.; Foods 12, 1278 (2023), Abstract;
Mycotoxin occurrence on baled and pit silages collected in Co. Meath: C. McElinney, et al.; Irish J. Agr. Food. Res. 54, 87 (2015), Application(s): Liquid chromatography tandem mass spectrometry for Mycotoxin analysis, Full Text
Cytotoxicity and related effects of T-2 toxin on cultured Vero cells: C. Bouaziz, et al.; Toxicon 48, 343 (2006), Abstract;
Development of apoptosis and changes in lymphocyte subsets in thymus, mesenteric lymph nodes and Peyer’s patches of mice orally inoculated with T-2 toxin: T. Nagata, et al.; Exp. Toxicol. Pathol. 53, 309 (2001), Abstract;
Kinetics of apoptosis-related genes mRNA expression in the dorsal skin of hypotrichotic WBN/ILA-ht rats after topical application of T-2 toxin: S.M. Albarenque, et al.; Exp. Toxicol. Pathol. 52, 553 (2001), Abstract;
Kinetics and distribution of transforming growth factor (TGF)-beta 1 mRNA in the dorsal skin of hypotrichotic WBN/ILA-Ht rats following topical application of T-2 toxin: S.M. Albarenque, et al.; Exp. Toxicol. Pathol. 52, 297 (2000), Abstract;
Thymocyte apoptosis by T-2 toxin in vivo in mice is independent of Fas/Fas ligand system: A.M. Murshedul, et al.; Biosci. Biotechnol. Biochem. 64, 210 (2000), Abstract;
T-2 toxin induces thymic apoptosis in vivo in mice: Z. Islam, et al.; Toxicol. Appl. Pharmacol. 148, 205 (1998), Abstract;
T-2 toxin-induced apoptosis in hematopoietic tissues of mice: J. Shinozuka, et al.; Toxicol. Pathol. 26, 674 (1998), Abstract;
Apoptotic cellular damage in mice after T-2 toxin-induced acute toxicosis: T. Ihara, et al.; Nat. Toxins 5, 141 (1997), Abstract;
T-2 toxin-induced apoptosis in lymphoid organs of mice: J. Shinozuka, et al.; Exp. Toxicol. Pathol. 49, 387 (1997), Abstract;
The structures of toxins from two strains of Fusarium tricinctum: J.R. Bamburg, et al.; Tetrahedron 24, 3329 (1968), Abstract;

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ALX-630-113-M005 5 mg 1,137.00 USD
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Monoamine oxidase
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Monoamine oxidase Inhibitor
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