Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 


ROS dye
ALX-620-061-M050 50 mg 48.00 USD
Do you need bulk/larger quantities?
Chemiluminescent probe for the detection of superoxide in biological systems.

Product Details

Alternative Name:bis-N-Methylacridinium nitrate, N,N'-Dimethyl-9,9'-biacridinium dinitrate
Purity:≥97% (HPLC)
Appearance:Off-white to brown powder.
Solubility:Soluble in DMSO (~12mg/ml), 100% ethanol (~0.5mg/ml) or acetic acid (~10mg/ml, heat up solution).
Shipping:Ambient Temperature
Long Term Storage:Ambient
Regulatory Status:RUO - Research Use Only
Please mouse over

Product Literature References

PKC/NADPH oxidase are involved in the protective effect of pioglitazone in high homocysteine-induced paracrine dyfunction in endothelial progenitor cells: S. Xu, et al.; Am. J. Transl. Res. 9, 1037 (2017), Abstract; Full Text
Globular adiponectin attenuates LPS-induced reactive oxygen species production in HepG2 cells via FoxO3A and HO-1 signaling: A. Shrestha & P.H. Park; Life Sci. 148, 71 (2016), Application(s): Cell culture, Abstract;
Crucial Role of Membrane Type 1 Matrix Metalloproteinase (MT1- MMP) in RhoA/Rac1-Dependent Signaling Pathways in Thrombin- Stimulated Endothelial Cells: K. Ando, et al.; J. Atheroscler. Thromb. 18, 762 (2011), Abstract; Full Text
In retinal vein occlusion platelet response to thrombin is increased: G. Leoncini, et al.; Thromb Res. 124, e48 (2009), Abstract;
Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation: M.M. Tarpey, et al.; Circ. Res. 84, 1203 (1999), Abstract;
Lucigenin as a substrate of microsomal NAD(P)H-oxidoreductases: I.A. Schepetkin; Biochemistry (Mosc.) 64, 25 (1999), Abstract;
Lucigenin is a mediator of cytochrome C reduction but not of superoxide production: I.B. Afanas'ev, et al.; Arch. Biochem. Biophys. 366, 267 (1999), Abstract;
Validation of lucigenin as a chemiluminescent probe to monitor vascular superoxide as well as basal vascular nitric oxide production: M.P. Skatchkov, et al.; BBRC 254, 319 (1999), Abstract;
Lucigenin as mediator of superoxide production: revisited: S.I. Liochev & I. Fridovich; Free Radic. Biol. Med. 25, 926 (1998), Abstract;
Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems: Y. Li, et al.; J. Biol. Chem. 273, 2015 (1998), Abstract; Full Text
What do we measure with luminol-, lucigenin- and penicillin-amplified chemiluminescence? 1. Investigations with hydrogen peroxide and sodium hypochlorite: M. Rost, et al.; J. Biolumin. Chemilumin. 13, 355 (1998), Abstract;

Related Products

Lucigenin (ultra pure) 

Chloride dye
22103-92-0, ≥98% (HPLC) | Print as PDF
ENZ-52154 10 mg 122.00 USD
Do you need bulk/larger quantities?

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
By catalog section:


Technical Service
Customer Service

Related Literature

Live Cell Analysis
Live Cell Analysis
Download as PDF

Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

All new literature pieces