Highly reactive fluorogenic reagent for labelling thiol compounds. Selectively labels protein cysteine residues without side chain modification or N-terminal blockage. Potent vasorelaxant.
Product Details
| Alternative Name: | 4-Fluoro-7-sulfoamoylbenzofurazan |
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| Formula: | C6H4FN3O3S |
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| MW: | 217.2 |
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| CAS: | 91366-65-3 |
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| Purity: | ≥99% (HPLC) |
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| Identity: | Determined by IR. |
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| Appearance: | White to yellow crystalline powder. |
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| Solubility: | Soluble in acetonitrile. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light and moisture. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Fluorometric assay of thiols with fluorobenzoxadiazoles: K. Imai and T. Toyo'oka; Meth. Enzymol.
143, 67 (1987),
Abstract;
Amino acid composition analysis of minute amounts of cysteine- containing proteins using 4-(aminosulfonyl)-7-fluoro-2,1,3- benzoxadiazole and 4-fluoro-7-nitro-2,1,3-benzoxadiazole in combination with HPLC: T. Toyo'oka, et al.; Biomed. Chromatogr.
1, 15 (1986),
Abstract;
Isolation and characterization of cysteine-containing regions of proteins using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and high- performance liquid chromatography: T. Toyo'oka and K. Imai; Anal. Chem. 57, 1931 (1985),
New Fluorogenic Reagent Having Halogenobenzofurazan Structure for Thiols: 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole: T. Toyo'oka and K. Imai; Anal. Chem. 56, 2461 (1984),
