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Acetylcholine receptor activator
ALX-550-520-M001 1 mg 204.00 USD
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Ligand of nicotinic acetylcholine receptors (nAChRs). Potent agonist of native and recombinant α4β2 nACHRs showing differential efficacy on α4β2 nAChRs subtypes.

Product Details

Formula:C15H20N2O2 . 2HCl
MW:260.3 . 73.0
Purity:≥95% (HPLC)
Appearance:White to off-white solid.
Solubility:Soluble in DMSO, methanol or water.
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Sazetidine-A is a potent and selective agonist at native and recombinant alpha4beta2 nicotinic acetylcholine receptors: R. Zwart, et al.; Mol. Pharmacol. 73, 1838 (2008), Abstract;
Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them: Y. Xiao, et al.; Mol. Pharmacol. 70, 1454 (2006), Abstract; Full Text

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