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MDL 105,212 . hydrochloride

Tachykinin antagonist



ALX-550-357-M001	1 mg	50.00 USD
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Non-peptide tachykinin antagonist with high affinity for NK₁ and NK₂ receptors.

Product Details

Formula:	C₃₄H₃₉Cl₂N₃O₅ . HCl

MW:	640.6 . 36.5

CAS:	167261-59-8

Purity:	≥97% (TLC)

Identity:	Determined by NMR.

Appearance:	Off-white solid.

Solubility:	Soluble in water.

Shipping:	Ambient

Long Term Storage:	+4°C

Regulatory Status:	RUO - Research Use Only

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Product Literature References

Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model: E.M. Kudlacz, et al.; J. Pharmacol. Exp. Ther. 279, 732 (1996), Abstract;

Identification and chemical synthesis of MDL 105,212, a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors: T.P. Burkholder, et al.; Bioorg. Med. Chem. Lett. 6, 951 (1996),

In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist: E.M. Kudlacz, et al.; J. Pharmacol. Exp. Ther. 277, 840 (1996), Abstract;