Antagonist with different binding profiles towards the vanilloid receptor 1 (TRPV1).
Activator of TRPA1
Product Details
| Formula: | C15H20O2 |
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| MW: | 232.3 |
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| CAS: | 37841-91-1 |
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| Purity: | ≥99% |
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| Appearance: | White to off-white crystalline solid. |
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| Solubility: | Soluble in organic solvents. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
TRPA1 mediates the noxious effects of natural sesquiterpene deterrents: J. Escalera, et al.; J. Biol. Chem.
283, 24136 (2008),
Abstract;
Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors: V. Ralevic, et al.; Biochem. Pharmacol.
65, 143 (2003),
Abstract;
The preparation and bioactivities of (-)-isovelleral: M. Jonassohn, et al.; Bioorg. Med. Chem.
5, 1363 (1997),
Abstract;
The stimulation of capsaicin-sensitive neurones in a vanilloid receptor-mediated fashion by pungent terpenoids possessing an unsaturated 1,4-dialdehyde moiety: A. Szallasi, et al.; Br. J. Pharmacol.
119, 283 (1996),
Abstract;
Comparison of the antimicrobial and cytotoxic activities of twenty unsaturated sesquiterpene dialdehydes from plants and mushrooms: H. Anke & O. Sterner; Planta Med.
57, 344 (1991),
Abstract;
Fungal extractives I. structure of a sesquiterpene dialdehyde from Lactarius by computer simulation of the nmr spectrum: G. Magnusson, et al.; THL 13, 1105 (1972), (Isolation),
