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mGluR antagonist
ALX-550-312-M001 1 mg 35.00 USD
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The active isomer of (RS)-MPPG (Prod. No. ALX-550-122). Highly potent L-AP4-sensitive receptor antagonist.

Product Details

Alternative Name:(S)-α-Methyl-4-phosphonophenylglycine
Appearance:White powder.
Solubility:Soluble in dilute aqueous base.
Long Term Storage:+4°C
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Asymmetric Strecker-type reaction of alpha-aryl ketones. Synthesis of (S)-alphaM4CPG, (S)-MPPG, (S)-AIDA and (S)-APICA, the antagonists of metabotropic glutamate receptors: D. Ma, et al.; J. Org. Chem. 64, 120 (1999), Abstract;
Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia: A. de Mendonca & J.A. Ribeiro; Neuroreport 8, 3667 (1997), Abstract;
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord: D.E. Jane, et al.; Neuropharmacology 34, 851 (1995), Abstract;

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