The active isomer of (RS)-MPPG (Prod. No. ALX-550-122). Highly potent L-AP4-sensitive receptor antagonist.
Product Details
| Alternative Name: | (S)-α-Methyl-4-phosphonophenylglycine |
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| Formula: | C9H12NO5P |
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| MW: | 245.2 |
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| CAS: | 201608-25-5 |
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| Purity: | ≥97% |
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| Appearance: | White powder. |
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| Solubility: | Soluble in dilute aqueous base. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Asymmetric Strecker-type reaction of alpha-aryl ketones. Synthesis of (S)-alphaM4CPG, (S)-MPPG, (S)-AIDA and (S)-APICA, the antagonists of metabotropic glutamate receptors: D. Ma, et al.; J. Org. Chem.
64, 120 (1999),
Abstract;
Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia: A. de Mendonca & J.A. Ribeiro; Neuroreport
8, 3667 (1997),
Abstract;
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord: D.E. Jane, et al.; Neuropharmacology
34, 851 (1995),
Abstract;
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