Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Amiloride, 5-(N,N-Dimethyl)-, . hydrochloride

Na+/H+ antiporter inhibitor
ALX-550-261-M005 5 mg 72.00 USD
Do you need bulk/larger quantities?
Na+/H+ antiporter inhibitor (IC50=6.9 µM) with increased selectivity and potency relative to amiloride (Prod. No. ALX-550-212).

Product Details

Alternative Name:5-(N,N-Dimethyl)amiloride . HCl, DMA . HCl
Formula:C8H12ClN7O . HCl
MW:257.7 . 36.5
CAS:1214-79-5 (free base)
Purity:≥97% (TLC)
Appearance:Yellow solid.
Solubility:Soluble in methanol (10mg/ml) or water (6mg/ml).
Shipping:Ambient Temperature
Long Term Storage:+4°C
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
Please mouse over

Product Literature References

[6]-Gingerol Induces Amiloride-Sensitive Sodium Absorption in the Rat Colon via the Capsaicin Receptor TRPV1 in Colonic Mucosa: Y.Tsuchiya, et al.; J. Nutr. Sci. Vitaminol. (Tokyo) 64, 287 (2018), Abstract; Full Text
Effect of 5-(N,N-Dimethyl)-amiloride, a specific inhibitor of Na(+)/H(+) exchanger, on the palmitoyl-L-carnitine-induced mechanical and metabolic derangements in the isolated perfused rat heart: J. Arakawa & A. Hara; Pharmacology 59, 239 (1999), Abstract;
Hypericin-induced phototoxicity of human leukemic cell line HL-60 is potentiated by omeprazole, an inhibitor of H+K+-ATPase and 5'-(N,N-dimethyl)-amiloride, an inhibitor of Na+/H+ exchanger: L. Mirossay, et al.; Physiol. Res. 48, 135 (1999), Abstract;
Involvement of sodium in the protective effect of 5-(N,N-dimethyl)- amiloride on ischemia-reperfusion injury in isolated rat ventricular wall: H. Meng & G.N. Pierce; J. Pharmacol. Exp. Ther. 256, 1094 (1991), Abstract;
Amiloride and its analogs as tools in the study of ion transport: T.R. Kleyman & E.J. Cragoe Jr.; J. Membr. Biol. 105, 1 (1988), Abstract;

Related Products

Amiloride . hydrochloride . dihydrate 

Ca2+ channel inhibitor
17440-83-4, ≥98% (HPLC) | Print as PDF
ALX-550-212-G001 1 g 65.00 USD
Do you need bulk/larger quantities?

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

All new literature pieces