Selectively blocks L-type Ca2+ channels.
Product Details
| Alternative Name: | (α-3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile . HCl, D600, Gallopamil |
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| Formula: | C28H40N2O5 . HCl |
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| MW: | 521.1 |
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| CAS: | 16662-47-8 |
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| MI: | 14: 4356 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water or methanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | Ambient |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Mode of action and comparative efficacy of pharmacological agents that inhibit calcium-dependent dehydration of sickle cells: J.C. Ellory, et al.; Br. J. Pharmacol.
106, 972 (1992),
Abstract;
Physiological and pharmacological correlates of calcium antagonist receptors: J.A. Wagner, et al.; J. Cardiovasc. Pharmacol.
10, S1 (1987),
Abstract;
A pharmacological explanation of the use-dependency of the verapamil (and D-600) block of slow calcium channels: G.B. Frank; J. Pharmacol. Exp. Ther.
236, 505 (1986),
Abstract;
