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Loperamide . hydrochloride

Ca2+ channel blocker
ALX-550-253-G005 5 g 63.00 USD
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Non-selective Ca2+ channel blocker. At nanomolar concentrations, binds to opioid μ-receptors. Does not cross the blood brain barrier.

Product Details

Alternative Name:4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutyramide . HCl
Formula:C29H33ClN2O2 . HCl
MW:477.0 . 36.5
MI:14: 5571
Purity:≥98% (HPLC)
Appearance:White powder.
Solubility:Soluble in methanol or chloroform.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells: S. Zielke, et al.; Cell Death Dis. 9, 994 (2018), Abstract; Full Text
Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects: I.J. Reynolds, et al.; J. Pharmacol. Exp. Ther. 231, 628 (1984), Abstract;

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