K+ channel blocker. Antiarrhytmic. Cardiac depressant.
Product Details
| Alternative Name: | 4-Chloro-N,N-diethyl-N-heptylbenzenebutanaminium . tosylate |
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| Formula: | C21H37ClN . C7H7O3S |
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| MW: | 339.0 . 171.2 |
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| CAS: | 92953-10-1 |
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| Purity: | ≥95% (HPLC) |
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| Identity: | Determined by 1H-NMR. |
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| Appearance: | White solid. |
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| Solubility: | Soluble in water, methanol or DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis: N. Adragna, et al.; Front. Cell. Neurosci.
9, 255 (2015),
Application(s): Cell culture ,
Abstract;
The differential response of normal and ischaemic Purkinje fibres to clofilium, d-sotalol and bretylium: W.B. Gough & N. el-Sherif; Cardiovasc. Res.
23, 554 (1989),
Abstract;
Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked: J.P. Arena & R.S. Kass; Mol. Pharmacol.
34, 60 (1988),
Abstract;
