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L-703,606 . oxalate

NK1 receptor antagonist
ALX-550-201-M001 1 mg Inquire for pricing
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Potent and selective non-peptide NK1 tachykinin receptor antagonist.

Product Details

Alternative Name:cis-2-(Diphenylmethyl)-N-[(2-iodophenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine . oxalate
Formula:C27H29N2I . C2H2O4
MW:508.5 . 90.0
Identity:Determined by NMR.
Appearance:White to off-white solid.
Solubility:Soluble in methanol or DMSO; slightly soluble in water.
Long Term Storage:+4°C
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice - potential role of TRPA1 in osteoarthritis: L.J. Moilanen, et al.; Osteoarthritis Cartilage 23, 2017 (2015), Application(s): Cell culture , Abstract;
Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor: M.A. Cascieri, et al.; Mol. Pharmacol. 42, 458 (1992), Abstract;
Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor: T.M. Fong, et al.; J. Biol. Chem. 267, 25664 (1992), Abstract; Full Text

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