Potent L-AP4-sensitive receptor antagonist.
Product Details
| Alternative Name: | (RS)-α-Methyl-4-phosphonophenylglycine |
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| Formula: | C9H12NO5P |
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| MW: | 245.2 |
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| CAS: | 169209-65-8 |
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| Purity: | ≥97% |
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| Appearance: | White solid. |
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| Solubility: | Soluble in dilute aqueous base. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology
38, 1431 (1999),
Abstract;
Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia: A. de Mendonça & J.A. Ribeiro; Neuroreport
8, 3667 (1997),
Abstract;
Antagonism of the presumed presynaptic action of L-AP4 on GABAergic transmission in the ventrobasal thalamus by the novel mGluR antagonist MPPG: T.E. Salt & J.P. Turner; Neuropharmacology
35, 239 (1996),
Abstract;
Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors: J.S. Bedingfield, et al.; Eur. J. Pharmacol.
309, 71 (1996),
Abstract;
Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices: T.J. Bushell, et al.; Br. J. Pharmacol.
117, 1457 (1996),
Abstract;
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord: D.E. Jane, et al.; Neuropharmacology
34, 851 (1995),
Abstract;
