Replaces Prod. #: BML-CA210
Voltage-sensitive (L-type) Ca2+ channel blocker. Vasodilator. Induces apoptosis.
Product Details
| Formula: | C17H18N2O6 |
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| MW: | 346.3 |
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| CAS: | 21829-25-4 |
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| MI: | 14: 6528 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | Yellow crystalline powder. |
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| Solubility: | Soluble in acetone, chloroform or DMSO. Sparingly soluble in 100% ethanol. Insoluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Clostridioides difficile toxin B alone and with pro-inflammatory cytokines induces apoptosis in enteric glial cells by activating three different signalling pathways mediated by caspases, calpains and cathepsin B: K. Fettucciari, et al.; Cell. Mol. Life Sci.
79, 442 (2022),
Abstract;
Upregulation of Voltage-Gated Calcium Channel Cav1.3 in Bovine Somatotropes Treated with Ghrelin: V.M. Salinas Zarate, et al.; J. Signal Transduct.
2013, 527253 (2013),
Abstract;
Full Text
Stimulation of 5-HT(2) receptors in prefrontal pyramidal neurons inhibits Ca(v)1.2 L type Ca(2+) currents via a PLCbeta/IP3/calcineurin signaling cascade: M. Day, et al.; J. Neurophysiol.
87, 2490 (2002),
Application(s): Cell Culture,
Abstract;
Full Text
Multiple calcium channels and neuronal function: R.J. Miller; Science
235, 46 (1987),
Abstract;
Calcium antagonism and calcium entry blockade: T. Godfraind, et al.; Pharmacol. Rev.
38, 321 (1986),
Abstract;
