Selective GABAB receptor agonist. Skeletal muscle relaxant. The more active enantiomer of (±)-Baclofen (Prod. No. BML-EA128).
Product Details
| Alternative Name: | R-(+)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid . HCl, R-(+)-4-Amino-3-(4-chlorophenyl)butanoic acid . HCl |
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| Formula: | C10H12ClNO2 . HCl |
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| MW: | 213.7 . 36.5 |
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| CAS: | 63701-55-3 |
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| MI: | 14: 937 |
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| RTECS: | MW5084350 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water, dilute aqueous base or DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A novel cause of intrathecal baclofen overdosage: lessons to be learnt: C. Dalton, et al.; Clin. Rehabil.
22, 188 (2008),
Abstract;
Skeletal muscle relaxants: S. See & R. Ginzburg; Pharmacotherapy
28, 207 (2008),
Abstract;
Effects of GABA(B) receptor ligands in animal tests of depression and anxiety: M. Frankowska, et al.; Pharmacol. Rep.
59, 645 (2007),
Abstract;
Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat: Y.G. Hong & J.L. Henry; Eur. J. Pharmacol.
196, 267 (1991),
Abstract;
Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations: E. Falch, et al.; J. Neurochem.
47, 898 (1986),
Abstract;
3-(p-Chlorophenyl)-4-aminobutanoic acid--resolution into enantiomers and pharmacological activity: B. Witczuk, et al.; Pol. J. Pharmacol. Pharm.
32, 187 (1980),
Abstract;
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