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7-Chlorothiokynurenic acid . hydrochloride

NMDA receptor antagonist
ALX-550-067-M005 5 mg 44.00 USD
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NMDA receptor antagonist acting at the glycine site. More potent than the corresponding kynurenic acid analog (7-Chlorokynurenic acid . hydrochloride).

Product Details

Alternative Name:7-Chloro-4-mercaptoquinoline-2-carboxylic acid . HCl
Formula:C10H6ClNO2S . HCl
MW:239.7 . 36.5
Appearance:Yellow powder.
Solubility:Soluble in DMSO.
Long Term Storage:Ambient
Regulatory Status:RUO - Research Use Only
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Product Literature References

The glycine antagonist and free radical scavenger 7-Cl-thio-kynurenate reduces CA1 ischemic damage in the gerbil: D.E. Pellegrini-Giampietro, et al.; Neuroscience 63, 701 (1994), Abstract;
A study of the dose dependency of a glycine receptor antagonist in focal ischemia: J. Chen, et al.; J. Pharmacol. Exp. Ther. 267, 937 (1993), Abstract;
Thiokynurenates: a new group of antagonists of the glycine modulatory site of the NMDA receptor: F. Moroni, et al.; Eur. J. Pharmacol. 199, 227 (1991), Abstract;

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