Selective antagonist of the PI-linked metabotropic glutamate response.
Product Specification
| Alternative Name: | L(+)-2-Amino-3-phosphonopropanoic acid |
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| Formula: | C3H8NO5P |
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| MW: | 169.1 |
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| CAS: | 23052-80-4 |
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| Purity: | ≥97% |
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| Appearance: | White hygroscopic solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology
38, 1431 (1999), (Review),
Abstract;
Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation: J.J. O'Connor, et al.; Nature
367, 557 (1994),
Abstract;
Metabotropic glutamate receptors in brain function and pathology: D.D. Schoepp & P.J. Conn; TIPS
14, 13 (1993), (Review),
Abstract;
1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons: A.J. Irving, et al.; Eur. J. Pharmacol.
186, 363 (1990),
Abstract;
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid: D.D. Schoepp, et al.; Mol. Pharmacol.
38, 222 (1990),
Abstract;
