Replaces Prod. #: BML-CA400
Potent and selective NMDA receptor antagonist.
Product Details
| Alternative Name: | DL-2-Amino-5-phosphonopentanoic acid, DL-2-Amino-5-phosphonovaleric acid |
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| Formula: | C5H12NO5P |
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| MW: | 197.1 |
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| CAS: | 76326-31-3 |
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| Purity: | ≥99% (HPLC, TLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in 100mM NaOH or 25mM water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors: J.J. Hansen & P. Krogsgaard-Larsen; Med. Res. Rev.
10, 55 (1990),
Abstract;
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4- phosphonobutyrate in the cat spinal cord: J. Davies and J.C. Watkins; Brain Res.
235, 378 (1982),
Abstract;
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations: R.H. Evans, et al.; Br. J. Pharmacol.
75, 65 (1982),
Abstract;
2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation: J. Davies, et al.; Neurosci. Lett.
21, 77 (1981),
Abstract;
Excitatory amino acid transmitters: J.C. Watkins and R.H. Evans; Ann. Rev. Pharmacol. Toxicol.
21, 165 (1981), (Review),
Abstract;
