Active enantiomer of (R,S)-AMPA (Prod. No.
BML-EA110).
Product Details
| Alternative Name: | (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid |
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| Formula: | C7H10N2O4 |
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| MW: | 186.2 |
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| CAS: | 83643-88-3 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Identity determined by 1H-NMR. |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in water or dilute aqueous base. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats: H. Hara, et al.; Pharmacol. Biochem. Behav.
211, 173289 (2021),
Abstract;
HBT1, a Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Avoided Bell-Shaped Response in In Vitro BDNF Production: A. Kunagi, et al.; J. Pharmacol. Exp. Ther.
364, 377 (2019),
Abstract;
Full Text
Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology
38, 1431 (1999), (Review),
Abstract;
Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors: J. Lauridsen, et al.; J. Med. Chem.
28, 668 (1985),
Abstract;
Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid: J.J. Hansen, et al.; J. Med. Chem.
26, 901 (1983),
Abstract;
