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AMPA receptor agonist
ALX-550-016-M025 25 mg 978.00 USD
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Active enantiomer of (R,S)-AMPA (Prod. No. BML-EA110).

Product Details

Alternative Name:(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Purity:≥98% (HPLC)
Identity:Identity determined by 1H-NMR.
Appearance:White to off-white powder.
Solubility:Soluble in water or dilute aqueous base.
Shipping:Ambient Temperature
Long Term Storage:+4°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats: H. Hara, et al.; Pharmacol. Biochem. Behav. 211, 173289 (2021), Abstract;
HBT1, a Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Avoided Bell-Shaped Response in In Vitro BDNF Production: A. Kunagi, et al.; J. Pharmacol. Exp. Ther. 364, 377 (2019), Abstract; Full Text
Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology 38, 1431 (1999), (Review), Abstract;
Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors: J. Lauridsen, et al.; J. Med. Chem. 28, 668 (1985), Abstract;
Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid: J.J. Hansen, et al.; J. Med. Chem. 26, 901 (1983), Abstract;

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