Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

NADPH . tetrasodium salt

 
ALX-480-004-M050 50 mg 87.00 USD
 
ALX-480-004-M250 250 mg 289.00 USD
 
ALX-480-004-G001 1 g 929.00 USD
Do you need bulk/larger quantities?
 
NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of ROS (reactive oxygen species), allowing the regeneration of GSH (reduced glutathione). NADPH is also used for anabolic pathways, such as lipid synthesis, cholesterol synthesis, and fatty acid chain elongation.

The NADPH system is also responsible for generating free radicals in immune cells. These radicals are used to destroy pathogens in a process termed the respiratory burst. It is the source of reducing equivalents for cytochrome P450 hydroxylation of aromatic compounds, steroids, alcohols, and drugs.

Product Details

Alternative Name:β-Nicotinamide Adenine Dinucleotide Phosphate (reduced form) . 4Na, β-NADPH . 4Na
 
Formula:C21H26N7O17P3 . 4Na
 
MW:741.4 . 92.0
 
CAS:2646-71-1
 
Purity:≥95% (HPLC)
 
Appearance:White to light yellow powder.
 
Solubility:Soluble in water (50mg/ml) or 0.01M sodium hydroxide.
 
Shipping:Ambient Temperature
 
Long Term Storage:-20°C
 
Use/Stability:NADPH is unstable in acid media. Stock solutions should be at pH 8.
 
Handling:Protect from light.
 
Regulatory Status:RUO - Research Use Only
 
ALX-480-004
Please mouse over
ALX-480-004

Product Literature References

4-phenylbutyric acid - Identity crisis; can it act as a translation inhibitor?: D. Stein, et al.; Aging Cell 21, e13738 (2022), Abstract;
Anti-adiposity and lipid-lowering effects of schisandrol A in diet-induced obese mice: S.R. Kim, et al.; J. Food Biochem. 46, e14501 (2022), Abstract;
Anti-inflammatory effect of a triterpenoid from Balanophora laxiflora: results of bioactivity-guided isolation: T.D. Nguyen, et al.; Heliyon 8, e09070 (2022), Abstract;
Examining uncertainty in in vitro–in vivo extrapolation applied in fish bioconcentration models: H. Laue, et al.; Environ. Sci. Technol. 54, 9483 (2020), Abstract;
Repetitively Hypoxic Preconditioning Attenuates Ischemia/Reperfusion-Induced Liver Dysfunction Through Upregulation of Hypoxia-Induced factor-1 Alpha-Dependent Reversible Oxidative Modifications in Myoglobin and Functional Implications: M.H. Mannino, et al.; Antioxidants (Basel) 9, 549 (2020), Abstract; Full Text
Globular adiponectin attenuates LPS-induced reactive oxygen species production in HepG2 cells via FoxO3A and HO-1 signaling: A. Shrestha & P.H. Park; Life Sci. 148, 71 (2016), Application(s): Cell culture, Abstract;
Tales of Dihydrofolate Binding to R67 Dihydrofolate Reductase: M.R. Duff, et al.; Biochemistry 55, 133 (2016), Abstract; Full Text
Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme: K.R. Henne, et al.; Drug Metab. Dispos. 40, 1429 (2012), Abstract;
Efferent and afferent innervation of primate trabecular meshwork and scleral spur: J.M. Selbach, et al.; Invest. Ophthalmol. Vis. Sci. 41, 2184 (2000), Abstract; Full Text

Related Literature

Brochures
Genomics & Molecular Biology
Genomics & Molecular Biology
Download as PDF

All new literature pieces