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United States 

BMPO (high purity)

Spin trapping reagent
 
ALX-430-141-M010 10 mg 144.00 USD
 
ALX-430-141-M050 50 mg 523.00 USD
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Nitrone spin trap for the specific in vivo or in vitro detection of short-lived superoxide, hydroxyl and thiyl radicals. Forms distinguishable adducts which can be measured by EPR spectroscopy. Unlike with DMPO, the superoxide adduct does not decay into a hydroxyl adduct and it has a much longer half-life (t1/2=23min). Low paramagnetic impurities. No further purification required.

Product Specification

Alternative Name:5-tert-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide
 
Formula:C10H17NO3
 
MW:199.3
 
Purity:≥99% (HPLC)
 
Appearance:White to pinkish crystalline solid.
 
Solubility:Soluble in water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from moisture.
 
430-141
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430-141

Product Literature References

Reactive Oxygen Species Formed by Secondary Organic Aerosols in Water and Surrogate Lung Fluid: H. Tong, et al.; Environ. Sci. Technol. 52, 11651 (2018), Abstract;
Reactive oxygen species formed in aqueous mixtures of secondary organicaerosols and mineral dust influencing cloud chemistry and public health in the Anthropocene: H. Tong, et al.; Faraday Discuss. 200, 251 (2017), Application(s): ROS detection in aqueous mixtures of SOA by applying electron paramagnetic resonance (EPR) spectrometry, Abstract; Full Text
Oxidation of the Flavonolignan Silybin. In situ EPR Evidence of the Spin-Trapped Silybin Radical: R. Sokolova, et al.; Electrochim. Acta 205, 118 (2016), Application(s): in situ EPR spectroelectrochemistry,
Mechanism of the hydroxyl radical oxidation of methacryloyl peroxynitrate (MPAN) and its pathway toward secondary organic aerosol formation in the atmosphere: T.B. Nguyen, et al.; Phys. Chem. Chem. Phys. 17, 17914 (2015), Application(s): Trapping agent of OH radicals, Abstract; Full Text
S-allyl cysteine alleviates nonsteroidal anti-inflammatory drug-induced gastric mucosal damages by increasing cyclooxygenase-2 inhibition, heme oxygenase-1 induction, and histone deacetylation inhibition: J.M. Park, et al.; J. Gastroenterol. Hepatol. 29 Suppl. 4, 80 (2014), Application(s): Electron spin resonance (ESR) spectroscopy, Abstract;
Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence: H. Zhao, et al.; PNAS 102, 5727 (2005), Abstract;
Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species: H. Shi, et al.; Arch. Biochem. Biophys. 437, 59 (2005), Abstract;
Spin traps: in vitro toxicity and stability of radical adducts: N. Khan, et al.; Free Radic. Biol. Med. 34, 1473 (2003), Abstract;
Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals: H. Zhao, et al.; Free Radic. Biol. Med. 31, 599 (2001), Abstract;

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