Guanylyl cyclase activator. Cell permeable thiol-induced nitric oxide donor with strong vasodilator effects.
Product Specification
| Alternative Name: | 3-Bromo-4-methyl-3,4-hexamethylene-3,4-dihydrodiazete 1,2-dioxide |
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| Formula: | C7H11BrN2O2 |
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| MW: | 235.1 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White crystalline solid. |
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| Solubility: | Soluble in water (3.5mM), DMSO or 100% ethanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Thiol-induced nitric oxide release from 3-halogeno-3,4-dihydrodiazete 1,2-dioxides: I.A. Kirilyuk, et al.; J. Med. Chem.
41, 1027 (1998),
Abstract;
Kinetics of nitric oxide liberation by 3,4-dihydro-1,2-diazete 1,2- dioxides and their vasodilatory properties in vitro and in vivo: D.I. Utepbergenov, et al.; BBRC
214, 1023 (1995),
Abstract;
