Selective, cell permeable and non-toxic spin trap for peroxynitrite and secondary O-, C-, S-, and N- centered free radicals.
Product Details
| Alternative Name: | 2,2,4-Trimethyl-2H-imidazole-1-oxide |
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| Formula: | C6H10N2O |
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| MW: | 126.2 |
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| CAS: | 136440-22-7 |
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| Purity: | ≥98% (GLC) |
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| Appearance: | White to off-white crystalline solid. |
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| Solubility: | Soluble in DMSO, water, methanol or 100% ethanol. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light and moisture. Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Reassignment of organic peroxyl radical adducts: S.I. Dikalov & R.P. Mason; Free Radic. Biol. Med.
27, 864 (1999),
Abstract;
Formation of reactive oxygen species in various vascular cells during glyceryltrinitrate metabolism: S. Dikalov, et al.; J. Cardiovasc. Pharmacol. Ther.
3, 51 (1998),
Abstract;
Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine: S. Dikalov, et al.; BBRC
230, 54 (1997),
Abstract;
Spin trapping of superoxide radicals and peroxynitrite by 1-hydroxy-3-carboxy-pyrrolidine and 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants: S. Dikalov, et al.; BBRC
231, 701 (1997),
Abstract;
Determination of rate constants of the reactions of thiols with superoxide radical by electron paramagnetic resonance: critical remarks on spectrophotometric approaches: S. Dikalov, et al.; Arch. Biochem. Biophys.
326, 207 (1996),
Abstract;
Oxygen-centered spin adducts of 5,5-dimethyl-1-pyrroline N-oxide (DMPO) and 2H-imidazole 1-oxides: A.G. Krainev, et al.; J. Magn. Reson. B.
111, 272 (1996),
Abstract;
Spin trapping of O-, C-, and S-centered radicals and peroxynitrite by 2H-imidazole-1-oxides: S.I. Dikalov, et al.; BBRC
218, 616 (1996),
Abstract;
