Dissociates to sulfate and nitrous oxide in a pH-dependent manner following first order kinetics. Decomposition is also catalyzed by the borate anion. The half-life time is 7 min. at 37°C in 0.1M phosphate buffer, pH 7.4. Decomposition is nearly instantaneous at pH 5. Unlike other NONOates, Sulfo-NONOate produces nitrous oxide but not nitric oxide (NO) at physiological pH. Therefore it may be used as a negative control in experiments using other NO releasing NONOates.
Product Details
| Alternative Name: | Hydroxydiazenesulfonic acid 1-oxide . disodium salt |
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| Formula: | N2O5S . 2Na |
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| MW: | 140.1 . 46.0 |
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| CAS: | 61142-90-3 |
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| Purity: | ≥90% |
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| Appearance: | White to off-white crystalline solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light, air and moisture. Packaged under inert gas. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Complexes of .NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects: C.M. Maragos, et al.; J. Med. Chem.
34, 3242 (1991),
Abstract;
Kinetics of the boric acid catalyzed decomposition of the N-nitrosohydroxylamine-N-sulfonate ion: E.G. Switkes, et al.; Inorg. Chem.
12, 1120 (1973),
Abstract;
