Nitric oxide (NO) donor. The half-life time is 5 hours at 22°C in 0.1M phosphate buffer, pH 7.4. Decomposition of NONOates is nearly instantaneous at pH 5.0.
Product Details
| Alternative Name: | Dipropylenetriamine NONOate |
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| Formula: | C6H17N5O2 |
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| MW: | 191.2 |
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| CAS: | 146724-95-0 |
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| Purity: | ≥98% (NMR) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Highly soluble in water. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -80°C |
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| Handling: | Protect from light and moisture. Aqueous solutions should be prepared fresh daily. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Control of disease tolerance to malaria by nitric oxide and carbon monoxide: V. Jeney, et al.; Cell Rep.
8, 126 (2014),
Application(s): Injection of DPTA-NO and assessment with NO Detection Kit, cGMP Enzyme EIA,
Abstract;
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation. A novel antiapoptotic mechanism that suppresses apoptosis: N. Azad, et al.; J. Biol. Chem.
281, 34124 (2006),
Abstract;
In vitro cytotoxicity of glyco-S-nitrosothiols. a novel class of nitric oxide donors: H. Babich & H.L. Zuckerbraun; Toxicol. In Vitro
15, 181 (2001),
Abstract;
In vitro cytotoxicity of the nitric oxide donor, S-nitroso-N-acetyl-penicillamine, towards cells from human oral tissue: H. Babich, et al.; Pharmacol. Toxicol.
84, 218 (1999),
Abstract;
New Nitric Oxide-Releasing Zwitterions Derived from Polyamines: J.A. Hrabie, et al.; J. Org. Chem. 58, 1472 (1993),
