Nitric oxide (NO) donor. The half-life time of 0.1mM NOC-12 is 100 min. at 37°C in 0.1M PBS, pH 7.4.
Product Details
| Alternative Name: | 1-Hydroxy-2-oxo-3-(N-ethyl-2-aminoethyl)-3-ethyl-1-triazene |
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| Formula: | C6H16N4O2 |
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| MW: | 176.2 |
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| CAS: | 146724-89-2 |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in 0.1M NaOH (10mg/ml) |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Prepare fresh stock solution prior to use. Store in ice bath during the experiment. Stock solution will lose 5% of activity per day when stored at -20°C. |
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| Handling: | Protect from light and moisture. Packaged under inert gas. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Excellent absorption enhancing characteristics of NO donors for improving the intestinal absorption of poorly absorbable compound compared with conventional absorption enhancers: G. Fetih, et al.; Drug Metab. Pharmacokinet.
21, 222 (2006),
Abstract;
Full Text
Characterization of the influence of nitric oxide donors on intestinal absorption of macromolecules: K. Takahashi, et al.; Int. J. Pharm.
286, 89 (2004),
Abstract;
New nitric oxide-releasing zwitterions derived from polyamines: J.A. Hrabie, et al.; J. Org. Chem. 58, 1472 (1993),
