Selective substrate for nNOS (NOS I). 70% nitric oxide (NO) formation for nNOS (NOS I), 26% for eNOS (NOS III) and <0.5% for iNOS (NOS II) as compared to NO formation using NG-Hydroxy-L-arginine (NOHA, Prod No. ALX-106-004) as a substrate.
Product Specification
Formula: | C4H9N3O . HCl |
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MW: | 115.1 . 36.5 |
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CAS: | 551935-92-3 |
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Purity: | ≥95% (TLC, |
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Appearance: | White powder. |
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Solubility: | Soluble in water. |
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Shipping: | Ambient |
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Long Term Storage: | -20°C |
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Handling: | Very hygroscopic. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Isoform-selective substrates of nitric oxide synthase: Q. Jia, et al.; J. Med. Chem.
46, 2271 (2003),
Abstract;
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