Physiologically active nitric oxide (NO) releasing agent. Releasing one equivalent of NO the half life time at room temperature is ~40 minutes mostly independent from the pH.
Product Details
| Alternative Name: | 3-Morpholino-N-nitroso-aminoacetonitrile . γ-cyclodextrin complex |
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| CAS: | 26687-79-6 (SIN-1A) |
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| Quantity: | * Sold by net SIN-1A content. |
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| Formulation: | The complex contains 10 ± 2% of SIN-1A. SIN-1 content: not detectable. SIN-1C (N-morpholinoiminoacetonitrile) content: 0.5 ± 0.2%. |
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| Appearance: | Pale yellow powder. |
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| Solubility: | Well soluble in distilled water, isotonic saline, phosphate buffer or HCl solution, pH 1.4. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes: P.Y. Lum, et al.; Cell
116, 121 (2004),
Abstract;
The effects of molsidomine and its metabolite SIN-1 on coronary vessel tone, platelet aggregation, and eicosanoid formation in vitro--inhibition of 12-HPETE biosynthesis: H. Darius, et al.; J. Cardiovasc. Pharmacol.
6, 115 (1984),
Abstract;
