Antioxidant flavonoid. Anti-inflammatory compound. Chemopreventive agent. Decreases hepatic lipid synthesis.
Product Details
| Alternative Name: | (+)-Dihydroquercetin, (+)-3,3',4',5,7-Pentahydroxyflavanone, Taxifoliol, Distylin, Catechin hydrate |
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| Formula: | C15H12O7 |
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| MW: | 304.3 |
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| CAS: | 480-18-2 |
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| Purity: | ≥90% (HPLC) |
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| Appearance: | Light yellow to brown powder. |
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| Solubility: | Soluble in 100% ethanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The chemopreventive effect of taxifolin is exerted through ARE-dependent gene regulation: S.B. Lee, et al.; Biol. Pharm. Bull.
30, 1074 (2007),
Abstract;
Prevention of macrophage adhesion molecule-1 (Mac-1)-dependent neutrophil firm adhesion by taxifolin through impairment of protein kinase-dependent NADPH oxidase activation and antagonism of G protein-mediated calcium influx: Y.H. Wang, et al.; Biochem. Pharmacol.
67, 2251 (2004),
Abstract;
Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid: A. Theriault, et al.; J. Lipid Res.
41, 1969 (2000),
Abstract;
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radic. Biol. Med.
20, 933 (1996), (Review),
Abstract;
