Antioxidant flavonoid. Shows anti-proliferative and antitumor properties. Induces apoptosis. Induces cell cycle arrest at the G2/M phase. Anti-inflammatory compound. Suppresses NF-κB activation. Induces lipid peroxidation and DNA strand breaks.
Product Details
| Alternative Name: | 2’,3,4’,5,7-Pentahydroxyflavone |
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| Formula: | C15H10O7 |
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| MW: | 302.2 |
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| CAS: | 654055-01-3 |
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| MI: | 14: 6269 |
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| RTECS: | LK8749000 |
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| Purity: | ≥85% (HPLC) |
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| Appearance: | Yellow to brown. |
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| Solubility: | Soluble in methanol or 100% ethanol; slightly soluble in ether or acetic acid. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Morin (3,5,7,2’,4’-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosi: S.K. Manna, et al.; Clin. Cancer Res.
13, 2290 (2007),
Abstract;
Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway: H.M. Kuo, et al.; Anticancer Res.
27, 395 (2007),
Abstract;
Lipid peroxidation and DNA damage induced by morin and naringenin in isolated rat liver nuclei: S. C. Sahu & G. C. Gray; Food Chem. Toxicol.
35, 443 (1997),
Abstract;
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radic. Biol. Med.
20, 933 (1996), (Review),
Abstract;
