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Mitochondrial complex II inhibitor
ALX-380-316-M001 1 mg 238.00 USD
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Atpenin-related, specific inhibitor of complex II (succinate-ubiquinone oxidoreductase). Less potent than atpenins. Has antifungal, antibacterial and herbicidal activity. Inhibits the NADH-fumarate reductase activity of adult Ascaris suum mitochondria.

Product Details

Alternative Name:2-Hydroxy-5,6-dimethoxy-3-[(2R)-2-methylhex-4-enoyl]-1H-pyridin-4-one
Source:Isolated from Trichoderma harzianum FKI-1509.
Purity:≥95% (HPLC)
Appearance:White to off-white solid.
Solubility:Soluble in ethyl acetate or methanol; insoluble in water.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Technical Info/Product Notes:Manufactured with courtesy strain from The Kitasato Institute.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Factors affecting the production of Trichoderma harzianum secondary metabolites during the interaction with different plant pathogens: F. Vinale, et al.; Lett. Appl. Microbiol. 48, 705 (2009), Abstract;
Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase): H. Miyadera, et al.; PNAS 100, 473 (2003), Abstract;
Biological Activity of (-)-Harzianopyridone isolated from Trichoderma harzianum: H.G. Cutler & J.M. Jacyno; Agric. Biol. Chem. 55, 2629 (1991), Abstract; Full Text
Structure and biosynthesis of harzianopyridone, an antifungal metabolite of Trichoderma harzianum: J.M. Dickinson, et al.; J. Chem. Soc. 1885 (1989), Abstract;

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