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Fluoroquinolone antibacterial agent
ALX-380-287-G005 5 g 45.00 USD
ALX-380-287-G025 25 g 93.00 USD
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Fluoroquinolone antibacterial agent. Inhibits bacterial DNA gyrase (topoisomerase). Inhibits cell division and causes double-strand breaks in the bacterial chromosome. Broad-spectrum antibiotic effective against Gram-positive, Gram-negative and anaerobic bacteria. Effective against Mycobacterium tuberculosis. Potentially anxiogenic.

Product Details

Alternative Name:1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1- piperazinyl)-3-quinolinecarboxylic acid
MI:14: 2314
Purity:≥98% (HPLC)
Appearance:White to light yellow crystalline powder
Solubility:Soluble in dilute hydrochloric acid; insoluble in water.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Evaluating the Efficacy of Eravacycline and Omadacycline against Extensively Drug-Resistant Acinetobacter baumannii Patient Isolates: M.S. Deolankar, et al.; Antibiotics 11, 1298 (2022), Abstract;
Detection of microbial surface contamination and antibiotic resistant Escherichia coli on beef carcasses in Arusha, Tanzania: R. Murutu, et al.; Afr. J. Microbiol. Res. 10, 1148 (2016), Application(s): Determining antibiotic susceptibility, E. coli isolates, Full Text
In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates: A. AbdelKhalek, et al.; PLoS One 11, e0164227 (2016), Application(s): In vitro antibacterial activity of rhodanine compounds 1 to 7 against Bacillus anthracis, Abstract; Full Text
Anxiogenic potential of ciprofloxacin and norfloxacin in rats: S. Sen, et al.; Singapore Med. J. 48, 1028 (2007), Abstract; Full Text
Moxifloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis: evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy: R.K. Shandil, et al.; Antimicrob. Agents Chemother. 51, 576 (2007), Abstract; Full Text
Ciprofloxacin and norfloxacin, two fluoroquinolone antimicrobials: D.E. Nix & J.M DeVito; Clin. Pharm. 6, 105 (1987), Abstract;
Mechanisms of action of and resistance to ciprofloxacin: D.C. Hooper, et al.; Am. J. Med. 82, 12 (1987), Abstract;
Is ciprofloxacin active against clinically important anaerobes?: B. Watt & F.V. Brown; J. Antimicrob. Chemother. 17, 605 (1986), Abstract;

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Fluoroquinolone antibacterial agent
86393-32-0, ≥98% (HPLC) | Print as PDF
ALX-380-288-G005 5 g 46.00 USD
Do you need bulk/larger quantities?

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By target:
DNA gyrase
By biological activity:
DNA gyrase Inhibitor
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