Antibiotic. More hydrophobic analog of the antibiotic thiolutin (Prod. No.
BML-CT107) with selective antitumor activity. Potent inhibitor of bacterial and yeast RNA polymerases and of fungal mannan and glucan formation.
Product Specification
| Alternative Name: | Propionylpyrrothione, Farcinicin |
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| Formula: | C9H10N2O2S2 |
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| MW: | 242.3 |
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| Source: | Isolated from Streptomyces thioluteus. |
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| CAS: | 574-95-8 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Determined by 1H-NMR. |
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| Appearance: | Yellow to orange solid. |
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| Solubility: | Soluble in DMSO or dimethyl formamide; partially soluble in methanol or 100% ethanol; poorly soluble in water. |
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| Shipping: | Ambient |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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| Handling: | After reconstitution protect from light at -20°C. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Anticancer properties of dithiolopyrrolones: J.M. Webster, et al.; US Patent 6,020,360, (2000),
Studies on a common hydrolysis product of thiolutin and aureothricin: W.D. Celmer & I.A. Solomons; Antibiot. Annu. 622, (1953),
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