Analog of trichostatin A (Prod. No.
BML-GR309). Induces acetylation of histone H4. Shows antifungal activity.
Product Details
| Alternative Name: | Antibiotic 145-A |
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| Formula: | C23H32N2O8 |
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| MW: | 464.5 |
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| Source: | Isolated from Streptomyces sp. MST-AS5376. |
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| CAS: | 68676-88-0 |
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| MI: | 14: 9649 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation: T. Kohge, et al.; Biochem. Pharmacol.
56, 1359 (1998),
Abstract;
Effects of trichostatins on differentiation of murine erythroleukemia cells: M. Yoshida, et al.; Cancer Res.
47, 3688 (1987),
Abstract;
Full Text
Trichostatin C, a glucopyranosyl hydroxamate: N. Tsuji and M. Kobayashi: N. Tsuji and M. Kobayashi; J. Antibiot. (Tokyo)
31, 939 (1978),
Abstract;
