Antibiotic. Potent activator of the tipA gene, a bacterial transcription regulator involved in multidrug resistance.
Product Details
| Alternative Name: | 14-Demethylberinamycin |
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| Formula: | C50H49N15O15S |
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| MW: | 1132.1 |
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| Source: | Isolated from Streptomyces sp. MST-AS5991. |
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| CAS: | 158792-27-9 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white amorphous powder. |
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| Solubility: | Soluble in methanol, dimethyl formamide or DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators: J.D. Kahmann, et al.; EMBO J.
22, 1824 (2003),
Abstract;
Full Text
Microbial metabolites with tipA promoter inducing activity. II. Geninthiocin, a novel thiopeptide produced by Streptomyces sp. DD84: B.S. Yun, et al.; J. Antibiot. (Tokyo)
47, 969 (1994),
Abstract;
