Macrolide antibiotic with an unusual dimeric macrolide dilactone structure. Exhibited immunosuppressant activity in a NFAT-dependent transcription assay (IC50=0.63µg/ml).
Product Details
| Formula: | C28H38N2O6 |
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| MW: | 498.6 |
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| Source: | Isolated from Streptomyces conglobatus MST-AS5530. |
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| CAS: | 72263-05-9 |
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| RTECS: | JG7521800 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Simple aromatics identified with a NFAT-lacZ transcription assay for the detection of immunosuppressants: N.S. Burres, et al.; J. Antibiot. (Tokyo)
48, 380 (1995),
Abstract;
Conglobatin, a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005: J.W. Westley, et al.; J. Antibiot. (Tokyo)
32, 874 (1979),
Abstract;
