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Anguinomycin A

Antitumor antibiotic
 
ALX-380-202-MC01 0.1 mg 750.00 USD
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Antitumor antibiotic. Displays nanomolar cytotoxicity to murine P388 leukemia cells. Analog of leptomycin B (Prod. No. ALX-380-100), an inhibitor of nuclear protein export.

Product Details

Alternative Name:5-Demethylleptomycin A, KR 2827A
 
Formula:C31H44O6
 
MW:512.7
 
Source:Isolated from Streptomyces sp. MST-AS5546.
 
CAS:111278-01-4
 
Purity:≥95% (HPLC)
 
Appearance:Pale yellow film.
 
Solubility:Soluble in 100% ethanol (recommended) or methanol. Unstable in DMSO.
 
Shipping:Ambient Temperature
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
380-202
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380-202

Product Literature References

Anguinomycins C and D, new antitumor antibiotics with selective cytotoxicity against transformed cells: Y. Hayakawa, et al.; J. Antibiot. (Tokyo) 48, 954 (1995), Abstract;
New antitumor antibiotics, anguinomycins A and B: Y. Hayakawa, et al.; J. Antibiot. (Tokyo) 40, 1349 (1987), Abstract;

Related Products

Leptomycin B 

Nuclear export inhibitor
87081-35-4, Isolated from Streptomyces sp., ≥96% (HPLC) | Print as PDF
 
ALX-380-100-C100 100 µg 181.00 USD
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