Antifungal agent and respiration inhibitor. Acts by inhibiting mitochondrial respiration in fungi. Binds at the Q0-centre on cytochrome b and blocks the electron transfer between cytochrome b and cytochrome c1.
Product Details
| Alternative Name: | Methyl (2E,3Z,5E)-6-(4-chloro-3-methoxy-phenyl)-2-(methoxymethylidene)-3-methyl-hexa-3,5-dienoate |
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| Formula: | C17H19ClO4 |
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| MW: | 322.8 |
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| Source: | Isolated from Strobilurus sp. |
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| CAS: | 65105-52-4 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Determined by 1H-NMR. |
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| Appearance: | Light brown solid. |
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| Solubility: | Soluble in DMSO and methanol. |
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| Shipping: | Ambient |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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| Handling: | After reconstitution protect from light at -20°C. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin: R. S. Coleman & X. Lu; Chem. Commun. (Camb.)
2006, 423 (2006),
Abstract;
Strobilurins: Evolution of a New Class of Active Substances.: H. Sauter et al.; Angew. Chem. Int. Ed.
38, 1328 (1999),
Abstract;
Oudemansin, strobilurin A, strobilurin B and myxothiazol: new inhibitors of the bc1 segment of the respiratory chain with an E-beta-methoxyacrylate system as common structural element.: W. F. Becker et al.; FEBS Lett.
132, 329 (1981),
Abstract;
General Literature References
Review of strobilurin fungicide chemicals.: H. Balba; J Environ Sci Health B.
42, 441 (2007),
Abstract;
