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Strobilurin B

Antifungal agent
ALX-380-144-M001 1 mg 576.00 USD
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Antifungal agent and respiration inhibitor. Acts by inhibiting mitochondrial respiration in fungi. Binds at the Q0-centre on cytochrome b and blocks the electron transfer between cytochrome b and cytochrome c1.

Product Details

Alternative Name:Methyl (2E,3Z,5E)-6-(4-chloro-3-methoxy-phenyl)-2-(methoxymethylidene)-3-methyl-hexa-3,5-dienoate
Source:Isolated from Strobilurus sp.
Purity:≥97% (HPLC)
Identity:Determined by 1H-NMR.
Appearance:Light brown solid.
Solubility:Soluble in DMSO and methanol.
Short Term Storage:+4°C
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
Handling:After reconstitution protect from light at -20°C.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin: R. S. Coleman & X. Lu; Chem. Commun. (Camb.) 2006, 423 (2006), Abstract;
Strobilurins: Evolution of a New Class of Active Substances.: H. Sauter et al.; Angew. Chem. Int. Ed. 38, 1328 (1999), Abstract;
Oudemansin, strobilurin A, strobilurin B and myxothiazol: new inhibitors of the bc1 segment of the respiratory chain with an E-beta-methoxyacrylate system as common structural element.: W. F. Becker et al.; FEBS Lett. 132, 329 (1981), Abstract;

General Literature References

Review of strobilurin fungicide chemicals.: H. Balba; J Environ Sci Health B. 42, 441 (2007), Abstract;

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