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Antitumor antibiotic
ALX-380-115-M001 1 mg 388.00 USD
ALX-380-115-M005 5 mg 1,234.00 USD
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Antitumor antibiotic. Inhibits cell cycle at the G(2)/M phase and induces apoptosis.

Product Details

Alternative Name:NSC357683, XK 213
Source:Isolated from Streptomyces sp.
Purity:≥98% (HPLC)
Identity:Determined by 1H-NMR.
Appearance:White to off-white solid.
Solubility:Soluble in dimethyl formamide, methanol or water.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
Handling:After reconstitution protect from light at -20°C.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Echinosporins as new cell cycle inhibitors and apoptosis inducers from marine-derived Streptomyces albogriseolus: C.B. Cui, et al.; Fitoterapia 78, 238 (2007), Abstract;
Biosynthesis of the antibiotic echinosporin by a novel branch of the shikimate pathway: A. Dubeler; Eur. J. Org. Chem. 2002, 983 (2002),
Applications of an asymmetric [2 + 2]-photocycloaddition. Total synthesis of (-)-echinosporin. Construction of an advanced 11-deoxyprostaglandin intermediate: A. B. Smith; JACS 114, 2567 (1992),
Approaches to the total synthesis of the antitumor antibiotic echinosporin: M. A. Kinsella; J. Org. Chem. 55, 105 (1990),
Antitumor activity of echinosporin: M. Morimoto and R. Imai; J. Antibiot. 38, 490 (1985), Abstract;
A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization: T. Sato, et al.; J. Antibiot. 35, 266 (1982), Abstract;