Aminoglycoside antibiotic. Binds to the 70S ribosomal subunit. Inhibits translocation and elicits miscoding. Effective against Gram-negative and Gram-positive bacteria and mycoplasma.
Product Details
| Alternative Name: | Bekanamycin . sulfate |
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| Formula: | C18H37N5O10 . H2SO4 |
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| MW: | 581.6 |
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| Source: | Isolated from Streptomyces kanamyceticus. |
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| CAS: | 29701-07-3 |
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| MI: | 14: 5281 |
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| RTECS: | WK1976500 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White to off-white crystalline powder. |
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| Solubility: | Soluble in water (50mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
In vitro selection of RNA against kanamycin B: M. Kwon, et al.; Mol. Cells
11, 303 (2001),
Abstract;
Interaction of kanamycin A and kanamycin B with phospholipids: M.W. Yung & C. Green; J. Antibiot.
40, 862 (1987),
Abstract;
Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production: K. Basak & S.K. Majumdar; Antimicrob. Agents Chemother.
4, 6 (1973),
Abstract;
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The total synthesis of kanamycin B: S. Umezawa, et al.; J. Antibiot.
21, 424 (1968),
Abstract;
The Structure of Kanamycin B: T. Ito, et al.; J. Antibiot.
17, 189 (1964),
Abstract;
Studies on Streptomyces kanamyceticus, producer of kanamycin: Y. Okami, et al.; J. Antibiot.
12, 252 (1959),
Abstract;
